Screening Test for Inherited Diseases
STID is a screening test for hereditary diseases where the DNA of future parents is screened for 301 recessive hereditary diseases.
When both of the future parents are carrier of a gene mutation in the same disease gene, they have a 25% risk on children with a genetic disease. so prenatal diagnostics with chorion biopsy or amniocentesis is offered.
STID can be offered to any couple with the desire of having children as recessive diseases exist with healthy couples who are carrier of a mutation in the same gene without knowning it. The frequency of recessive diseases is 1%, which is higher than Down syndrome.
5 ml blood in an EDTA blood tube. Blood collection can be done at the GENDIA laboratory in Antwerp, or can me mailed to GENDIA. Samples should arrive within 48 hrs after withdrawal at room temperature. DNA samples (5 µg) can also be used for STID.
The report with the STID result takes about 1-2 months after arrival of the sample at GENDIA.
The STID is a DNA test with NGS sequencing and deletion-duplication analysis for 301 recessive hereditary diseases. The list of diseases can be viewed by clicking on “List of hereditary diseases”. The STID was developed and is performed by the Invitae laboratory in the USA under accreditation of Clinical Laboratory Improvement Amendments (CLIA).
The results will be mailed both to you and your physician by e-mail. Genetic counselling to discuss the results, implications towards your desire to have children and the organisation for further investigations are offered by GENDIA.
Only the genes involved in 301 frequent genetic diseases are analyzed. Some of the mutations in these 175 genes or mutations in other genes are not detected.
For this reason a normal STID result does not completely exclude that person of being a carrier for one of the analysed diseases.
Your sample and DNA will be used for the STID test only. Your DNA will be kept in the laboratory. The results of the STID test will be kept at GENDIA and in the laboratory.
GENDIA will meet Belgian and EU legislation and regulations concerning the protection and privacy of personal data and the collection, use, processing, saving and storing of patient data.
The results of the STID test will only be reported to you, not to any third party, including family members, insurance companies or physicians, unless requested by you.
As STID is a screening test which can be offered to any couple planning children with the desire of having children, a consultation is not necessary.
When both partners are carrier of a mutation in the same gene, a consultation is highly recommended.
You can make an appointment with GENDIA through email@example.com.
There are 2 possibilities:
- Consultation in Antwerp:
You can make an appointment for a consultation and a blood collection at the GENDIA premises in Antwerp through firstname.lastname@example.org.
Please fill out the form on your PC, print it out and bring it to the consultation.
- Sent a blood sample to GENDIA in Antwerp:
You or your physician can also sent out blood (5ml EDTA blood) to GENDIA in Antwerp. NEVER freeze the blood sample but sent it at room temperature.
Please fill out the form on your PC, print it out and sent it together with the blood sample to:
Emiel Vloorsstraat 9
The price of the STID without consultation is 390 Euro.